Response to Ernst Alexander’s comments

Response to Reviewers ’ Comments

Response to Reviewer’s Comments

#2. It is unclear why the authors only consider dust: the same problem should exist for other sources of iron as well, or probably even worse, especially finer particles from combustion? Why not consider those? You could presumably do this rather easily, just assuming BC has Fe, and including the size distribution of BC? There are recent reviews of the size of combustion iron particles (e.g. Wa...

Response to Reviewer Comments

Given d > 2 and a set of n grid points Q in R, we design a randomized algorithm that finds a w-wide separator, which is determined by a hyper-plane, in O(n 2 d log n) sublinear time such that Q has at most ( d d+1 + o(1))n points one either side of the hyper-plane, and at most cdwn d−1 d points within w 2 distance to the hyper-plane, where cd is a constant for fixed d. In particular, c3 = 1.209...

Response to Reviewers ' Comments :

We now continued our search in the 609 bp 3'-UTR region of GATA4 to explore further molecular avenues leading to CHD. Background: To identify further genetic alterations associated with CHD, we continued our search in the 609 bp of 3'-untranslated region (3'-UTR) of GATA4. 2. The authors should modify Table 3, indicating with a different character (for example in bold) the new sequence variatio...

Response to Reviewers ’ Comments